{"id":4414731,"date":"2026-02-03T15:17:59","date_gmt":"2026-02-03T19:17:59","guid":{"rendered":"https:\/\/epithelia.ca\/?p=4414731"},"modified":"2026-02-09T16:04:59","modified_gmt":"2026-02-09T20:04:59","slug":"how-digestive-health-can-contribute-to-immunity","status":"publish","type":"post","link":"https:\/\/epithelia.ca\/en\/blog\/how-digestive-health-can-contribute-to-immunity\/","title":{"rendered":"How can digestive health contribute to immunity?"},"content":{"rendered":"<p>[et_pb_section fb_built=\u00a0\u00bb1&Prime; _builder_version=\u00a0\u00bb4.27.5&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_row _builder_version=\u00a0\u00bb4.27.5&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_column type=\u00a0\u00bb4_4&Prime; _builder_version=\u00a0\u00bb4.27.5&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_text _builder_version=\u00a0\u00bb4.27.5&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb hover_enabled=\u00a0\u00bb0&Prime; global_colors_info=\u00a0\u00bb{}\u00a0\u00bb sticky_enabled=\u00a0\u00bb0&Prime;]<\/p>\n<p><span style=\"font-weight: 400;\">Ce qui se passe dans l\u2019intestin et plus pr\u00e9cis\u00e9ment, au sein du microbiote intestinal a diff\u00e9rents impacts sur la sant\u00e9 globale. D\u00e9taillons ensemble ses r\u00f4les sur le syst\u00e8me immunitaire!<\/span><\/p>\n<p><b>Qu\u2019est-ce que le syst\u00e8me immunitaire et \u00e0 quoi sert-il?<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Le syst\u00e8me immunitaire prot\u00e8ge l&rsquo;organisme contre les infections et autres agressions (4). Cela regroupe des barri\u00e8res physiques (ex. peau, muqueuses des voies gastro-intestinales et respiratoires) et biochimiques (ex. s\u00e9cr\u00e9tions, mucus, acide gastrique), de nombreuses cellules immunitaires diff\u00e9rentes (ex. granulocytes, lymphocytes B et T) et des anticorps (ex. immunoglobulines) (4).<\/span><\/p>\n<p><b>Quels sont les liens entre le microbiote intestinal et le syst\u00e8me immunitaire?<\/b><\/p>\n<p><i><span style=\"font-weight: 400;\">Saviez-vous que 70 % des cellules immunitaires du corps se retrouvent dans l\u2019intestin <\/span><\/i><span style=\"font-weight: 400;\">(1, 4)<\/span><i><span style=\"font-weight: 400;\">?<\/span><\/i><\/p>\n<p><span style=\"font-weight: 400;\">En effet, <a href=\"https:\/\/epithelia.ca\/lexique-de-la-sante-intestinale\">le microbiote<\/a><\/span><span style=\"font-weight: 400;\">\u00a0joue plusieurs r\u00f4les essentiels dans l\u2019immunit\u00e9 (1, 4).\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Il agit comme premi\u00e8re ligne de d\u00e9fense contre les agents pathog\u00e8nes (nuisibles) (1, 4, 8). Les \u00ab\u00a0bonnes\u00a0\u00bb bact\u00e9ries forment la barri\u00e8re intestinale, emp\u00eachant les bact\u00e9ries pathog\u00e8nes de s\u2019installer dans l\u2019intestin (1, 4, 8). La pr\u00e9sence d\u2019une couche de mucus contribue \u00e0 limiter la croissance des bact\u00e9ries et des substances nuisibles (1, 2, 4, 8).\u00a0\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Il aide \u00e0 \u00ab \u00e9duquer \u00bb et \u00e0 activer les cellules immunitaires distinguant les \u00e9l\u00e9ments b\u00e9n\u00e9fiques de ceux qui sont nuisibles (1, 4, 8).<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Il contribue \u00e0 moduler <a href=\"https:\/\/epithelia.ca\/blogue\/alimentation-anti-inflammatoire-un-terme-tendance-ou-concret\">l\u2019inflammation<\/a><\/span><span style=\"font-weight: 400;\">\u00a0(1). En effet, la pr\u00e9sence d\u2019une dysbiose (d\u00e9s\u00e9quilibre des bact\u00e9ries intestinales) affaiblit l\u2019immunit\u00e9 et favorise des processus inflammatoires dans le corps (1).\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Il synth\u00e9tise des substances favorables \u00e0 l\u2019immunit\u00e9 comme des mol\u00e9cules antimicrobiennes (bact\u00e9riocines) qui peuvent <\/span><i><span style=\"font-weight: 400;\">tuer<\/span><\/i><span style=\"font-weight: 400;\"> les bact\u00e9ries nuisibles (3). Le microbiote favorise aussi la production d\u2019acides gras \u00e0 cha\u00eene courte <a href=\"https:\/\/epithelia.ca\/lexique-de-la-sante-intestinale\">(<\/a><\/span><b>AGCC<\/b><span style=\"font-weight: 400;\">), jouant un r\u00f4le dans la r\u00e9ponse immunitaire du corps (1, 3, 5).\u00a0\u00a0\u00a0<\/span><\/li>\n<\/ul>\n<p>[\/et_pb_text][et_pb_text _builder_version=\u00a0\u00bb4.27.5&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb]<\/p>\n<h3><b>Comment am\u00e9liorer la sant\u00e9 du microbiote pour soutenir l\u2019immunit\u00e9?\u00a0<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">\u00c9tant donn\u00e9 que le microbiote est influenc\u00e9 par l\u2019<\/span><b>alimentation <\/b><span style=\"font-weight: 400;\">et les <\/span><b>habitudes de vie<\/b><span style=\"font-weight: 400;\">, certaines recommandations nutritionnelles peuvent aider la sant\u00e9 digestive et l\u2019immunit\u00e9.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Les termes \u00ab\u00a0renforcer le syst\u00e8me immunitaire\u00a0\u00bb sont souvent controvers\u00e9s. En fait, on ne souhaite pas booster le syst\u00e8me immunitaire, car on ne veut pas qu\u2019il travaille plus que suppos\u00e9. On veut plut\u00f4t lui donner toutes les chances de bien travailler. Et du c\u00f4t\u00e9 nutrition, certains nutriments sont cl\u00e9s\u00a0:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Une <\/span><b>alimentation riche en fibres alimentaires<\/b><span style=\"font-weight: 400;\"> et en pr\u00e9biotiques contribue \u00e0 pr\u00e9server une barri\u00e8re intestinale saine et une couche de mucus optimale, att\u00e9nuant les infections pathog\u00e8nes (2, 7)<\/span>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">\u00c0 l\u2019inverse\u00a0: Une alimentation pauvre en fibres favorise la prolif\u00e9ration et l&rsquo;activit\u00e9 des bact\u00e9ries qui d\u00e9gradent le mucus (2)\u00a0<\/span>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"3\"><span style=\"font-weight: 400;\">Donc moins de fibres = couche de mucus plus mince = barri\u00e8re intestinale moins efficace contre les agents pathog\u00e8nes!<\/span><\/li>\n<\/ul>\n<\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">La synth\u00e8se des <\/span><b>AGCC<\/b><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">lien lexique<\/span><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/epithelia.ca\/lexique-de-la-sante-intestinale\/\"><span style=\"font-weight: 400;\">https:\/\/epithelia.ca\/lexique-de-la-sante-intestinale\/<\/span><\/a><span style=\"font-weight: 400;\">) par la fermentation de ces aliments contribue \u00e9galement \u00e0 la r\u00e9ponse immunitaire du corps, entre autres, par la production et la s\u00e9cr\u00e9tion du mucus intestinal (7).<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">En bref, un microbiote intestinal sain maintient une relation symbiotique au sein de la muqueuse intestinale, assurant des fonctions essentielles dans le m\u00e9tabolisme, l&rsquo;immunit\u00e9 et la protection de l&rsquo;h\u00f4te (7).<\/span><b>\u00a0<\/b><\/p>\n<p><b>Ainsi, on mise sur tous les aliments favorables \u00e0 un microbiote intestinal \u00e9quilibr\u00e9 et on r\u00e9duit ceux qui lui nuisent (<\/b><span style=\"font-weight: 400;\">7)<\/span><b>.<\/b><\/p>\n<p><span style=\"font-weight: 400;\">On vise \u00e0\u00a0(6, 7):<\/span><\/p>\n<p><b>\u2191 la consommation de\u00a0:<\/b><\/p>\n<p><b>Om\u00e9ga-3<\/b><span style=\"font-weight: 400;\">\u00a0: poissons gras (saumon, truite, thon, sardines, maquereau, hareng), graines de lin\/de chia\/de chanvre\/de cam\u00e9line, noix de Grenoble, graines de citrouille\/de tournesol<\/span><\/p>\n<p><b>Fibres alimentaires<\/b><span style=\"font-weight: 400;\">\u00a0: l\u00e9gumes, fruits, grains entiers (bl\u00e9 entier, avoine, quinoa, orge mond\u00e9, sarrasin, riz brun), noix, graines, l\u00e9gumineuses (pois chiches, lentilles, haricots), edamames<\/span><\/p>\n<p><b>Prot\u00e9ines v\u00e9g\u00e9tales<\/b><span style=\"font-weight: 400;\">\u00a0: l\u00e9gumineuses (pois chiches, lentilles, haricots), tofu, edamames, prot\u00e9ines v\u00e9g\u00e9tales textur\u00e9es (PVT), tempeh, noix, graines<\/span><\/p>\n<p><b>\u2193 la consommation de\u00a0:<\/b><\/p>\n<p><b>Acides gras satur\u00e9s<\/b><span style=\"font-weight: 400;\">\u00a0: viandes rouges (b\u0153uf, porc, veau, agneau), charcuteries, huile de palme, saindoux, shortening\u00a0<\/span><\/p>\n<p><b>Aliments riches en sucres ajout\u00e9s<\/b><span style=\"font-weight: 400;\">\u00a0: bonbons, desserts (g\u00e2teau, beignes, biscuits, p\u00e2tisseries), chocolat, cr\u00e8me glac\u00e9e, boissons gazeuses, cocktails de fruits<\/span><\/p>\n<p><b>Aliments ayant des additifs alimentaires et des \u00e9dulcorants<\/b><span style=\"font-weight: 400;\"> (ex. carboxym\u00e9thylcellulose, polysorbate 80, aspartame, sucralose, saccharine)\u00a0: bonbons, desserts, g\u00e2teaux, biscuits, plats pr\u00e9par\u00e9s, sauces, vinaigrette, cr\u00e8me glac\u00e9e, produits all\u00e9g\u00e9s ou sans sucre comme les boissons gazeuses, eaux aromatis\u00e9es, boissons sportives.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">En bref, viser une <\/span><b>alimentation \u00e9quilibr\u00e9e riche en l\u00e9gumes et en fruits<\/b><span style=\"font-weight: 400;\"> est favorable pour l\u2019immunit\u00e9. Une <\/span><b>alimentation diversifi\u00e9e<\/b><span style=\"font-weight: 400;\"> bas\u00e9e sur l\u2019<\/span><b>alimentation m\u00e9diterran\u00e9enne <\/b><span style=\"font-weight: 400;\">aide \u00e0 retrouver tous les nutriments cl\u00e9s ainsi qu\u2019 \u00e0 favoriser une plus grande diversit\u00e9 de bact\u00e9ries intestinales (6).\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Vous cherchez des recettes pour int\u00e9grer tous ces aliments favorables?\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Devenez abonn\u00e9.e aux recettes exclusives sign\u00e9es Epith\u00e9lia! <a href=\"https:\/\/epithelia.ca\/produit\/abonnement-annuel-a-notre-banque-de-recettes\"><strong>PAR ICI pour l&rsquo;abonnement!<\/strong><\/a><\/span><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=\u00a0\u00bb4.27.5&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb hover_enabled=\u00a0\u00bb0&Prime; global_colors_info=\u00a0\u00bb{}\u00a0\u00bb sticky_enabled=\u00a0\u00bb0&Prime;]<\/p>\n<p><b>R\u00e9f\u00e9rences<\/b><\/p>\n<ol>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cristofori et al. (2021) Anti-Inflammatory and Immunomodulatory Effects of Probiotics in Gut Inflammation: A Door to the Body. Front Immunol Feb 26;12:578386. <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33717063\/\"><span style=\"font-weight: 400;\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33717063\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Desai et al. (2016) A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility. Cell Nov 17;167(5):1339-1353.e21. <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27863247\/\"><span style=\"font-weight: 400;\">https:\/\/pubmed.ncbi.nlm.nih.gov\/27863247\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fondation Canadienne de la Sant\u00e9 Digestive (2023) Comment l\u2019alimentation peut-elle favoriser la sant\u00e9 intestinale et le syst\u00e8me immunitaire?, en ligne, <\/span><a href=\"https:\/\/cdhf.ca\/fr\/comment-lalimentation-peut-elle-favoriser-la-sante-intestinale-et-le-systeme-immunitaire\/\"><span style=\"font-weight: 400;\">https:\/\/cdhf.ca\/fr\/comment-lalimentation-peut-elle-favoriser-la-sante-intestinale-et-le-systeme-immunitaire\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Maggini et al. (2018) Immune Function and Micronutrient Requirements Change over the Life Course. Nutrients Oct 17;10(10):1531. <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30336639\/\"><span style=\"font-weight: 400;\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30336639\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mazziotta et al. (2023) Probiotics Mechanism of Action on Immune Cells and Beneficial Effects on Human Health Cells Jan 2;12(1):184. <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36611977\/\"><span style=\"font-weight: 400;\">https:\/\/pubmed.ncbi.nlm.nih.gov\/36611977\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rinninella et al. (2023) The role of diet in shaping human gut microbiota. Best Pract Res Clin Gastroenterol Feb-Mar;62-63:101828. <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37094913\/\"><span style=\"font-weight: 400;\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37094913\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Statovci et al. (2017) The Impact of Western Diet and Nutrients on the Microbiota and Immune Response at Mucosal Interfaces. Front Immunol Jul 28;8:838. <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28804483\/\"><span style=\"font-weight: 400;\">https:\/\/pubmed.ncbi.nlm.nih.gov\/28804483\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Yan et Polk (2011) Probiotics and immune health. Curr Opin Gastroenterol Oct;27(6):496-501. <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21897224\/\"><span style=\"font-weight: 400;\">https:\/\/pubmed.ncbi.nlm.nih.gov\/21897224\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<\/ol>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ce qui se passe dans l\u2019intestin et plus pr\u00e9cis\u00e9ment, au sein du microbiote intestinal a diff\u00e9rents impacts sur la sant\u00e9 globale. D\u00e9taillons ensemble ses r\u00f4les sur le syst\u00e8me immunitaire! Qu\u2019est-ce que le syst\u00e8me immunitaire et \u00e0 quoi sert-il? Le syst\u00e8me immunitaire prot\u00e8ge l&rsquo;organisme contre les infections et autres agressions (4). Cela regroupe des barri\u00e8res physiques [&hellip;]<\/p>\n","protected":false},"author":1802,"featured_media":4414732,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","wprm-recipe-roundup-name":"","wprm-recipe-roundup-description":"","footnotes":""},"categories":[24,1704],"tags":[],"class_list":["post-4414731","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blogue","category-sante-digestive"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/epithelia.ca\/en\/wp-json\/wp\/v2\/posts\/4414731","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/epithelia.ca\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/epithelia.ca\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/epithelia.ca\/en\/wp-json\/wp\/v2\/users\/1802"}],"replies":[{"embeddable":true,"href":"https:\/\/epithelia.ca\/en\/wp-json\/wp\/v2\/comments?post=4414731"}],"version-history":[{"count":6,"href":"https:\/\/epithelia.ca\/en\/wp-json\/wp\/v2\/posts\/4414731\/revisions"}],"predecessor-version":[{"id":4414871,"href":"https:\/\/epithelia.ca\/en\/wp-json\/wp\/v2\/posts\/4414731\/revisions\/4414871"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/epithelia.ca\/en\/wp-json\/wp\/v2\/media\/4414732"}],"wp:attachment":[{"href":"https:\/\/epithelia.ca\/en\/wp-json\/wp\/v2\/media?parent=4414731"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/epithelia.ca\/en\/wp-json\/wp\/v2\/categories?post=4414731"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/epithelia.ca\/en\/wp-json\/wp\/v2\/tags?post=4414731"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}